News

Coinfection: More than the sum of its parts

Infections with two pathogens pose a serious threat in the clinics. Researchers from Würzburg and Jena have developed a technique that provides new insights into this process and can be used as an early warning system. Organ and stem cell transplants are proven and frequently used methods in everyda…

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Antibiotics affect balance of intestinal microbiome

Treatment with antibiotics has a lasting effect on the microbiome in the digestive system. While the bacterial flora is largely regenerated within 30 to 90 days after drug treatment, its interaction with resident fungi changes. In a combination of bioinformatic analyses and laboratory experiments, a…

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Fungus delays immune response

Extracellular vesicles - small, membrane-enclosed particles secreted by cells - are important components of cell communication and interaction. For example, they transport messenger substances from cell to cell. What role they play in the interaction of the pathogenic yeast fungus Candida albicans w…

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Report about Publication of Project A3

In its current issue, the journal Nature Reviews Microbiology reports about the recent mBio research article of Project A3 advancing light-sheet fluorescence microscopy (LSFM) to study host-fungal pathogen interactions within the 3D environment of the lung. In the news section Under the Lens, Manish…

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New Publication by Project A3

This publication reports for the first time the successful application of expansion microscopy (ExM) to fungi, allowing for visualising cellular structures with a spatial resolution of ≤60 nm with a confocal fluorescence microscope. Access to super-resolution microscopy setups is often limited, wher…

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Can the microbiome lead to a therapy prognosis for cancer in the future?

Cancer patients respond differently to therapies and the success of common treatments possibly depends on the composition of the intestinal microbiomes. This is the conclusion of researchers from Jena and Hong Kong, including Dr. Gianni Panagiotou of the FungiNet consortium (Project B5), and is base…

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Fight diabetes with exercise

A common advice by GPs to patients diagnosed with prediabetes is to perform light exercise. Often this slows down or even stops the progression to type 2 diabetes. But not every patient reacts positively to exercise. A study led by Gianni Panagiotou, a computational biologist from Jena and Principal…

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Report: Molecular Mycology (MOMY) course at Marine Biological Laboratory in Woods Hole

Esther Weiss, Doctoral researcher in Project A2, was lucky to attend the Molecular Mycology (MOMY) course July 17 – August 2, 2019 at the Marine Biological Laboratory in Woods Hole, Massachusetts, USA. In a group of 18 students, she learned cutting-edge methods, e.g., gene manipulation of Candida, C…

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2nd Industry Contact Forum

The 2nd Industry Contact Forum held on June 27, 2019 provided an opportunity of early career researchers to explore non-academic career trajectories. Experts in diverse fields such as start-up businesses, pharmaceutical research & development, federal consumer protection & food safety, as well a…

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