News
Alternative energy in the fungal cell
Until now, almost all studies suggested that the formation of hyphae is one of the most important virulence factors of the yeast Candida albicans. Ilse Jacobsen, Project leader of FungiNet Project C5 at Leibniz-HKI and her team in in Jena – in close collaboration with the group of Thomas Dandekar wi…
TRR 124 FungiNet granted DFG funding for a further four years
The German Research Foundation (DFG) will fund the Collaborative Research Center/Transregio (CRC/TR) “FungiNet” for four more years with approximately ten million Euro. In the only CRC studying human pathogenic fungi, scientists in Jena and Würzburg will investigate infection processes and novel the…
more… TRR 124 FungiNet granted DFG funding for a further four years
Cellular altruism
Candida albicans forms filaments on epithelial cells that help the fungus attach and cause infections. Infections caused by yeasts of the genus Candida trigger an immune response that was previously known only in the defense against viruses, bacteria or parasites. A research team from Jena including…
Wissenschaftler:innen und Karriere Jena
The Deutsche Forschungsgemeinschaft (DFG) promotes equal opportunities for scientists in its programmes. In order to pool and use the equal opportunities funds of coordinated programmes for targeted and tailored measures, the association "Wissenschaftler:innen und Karriere Jena" („Scientists and Car…
Coinfection: More than the sum of its parts
Infections with two pathogens pose a serious threat in the clinics. Researchers from Würzburg and Jena have developed a technique that provides new insights into this process and can be used as an early warning system. Organ and stem cell transplants are proven and frequently used methods in everyda…
Antibiotics affect balance of intestinal microbiome
Treatment with antibiotics has a lasting effect on the microbiome in the digestive system. While the bacterial flora is largely regenerated within 30 to 90 days after drug treatment, its interaction with resident fungi changes. In a combination of bioinformatic analyses and laboratory experiments, a…
Fungus delays immune response
Extracellular vesicles - small, membrane-enclosed particles secreted by cells - are important components of cell communication and interaction. For example, they transport messenger substances from cell to cell. What role they play in the interaction of the pathogenic yeast fungus Candida albicans w…
Report about Publication of Project A3
In its current issue, the journal Nature Reviews Microbiology reports about the recent mBio research article of Project A3 advancing light-sheet fluorescence microscopy (LSFM) to study host-fungal pathogen interactions within the 3D environment of the lung. In the news section Under the Lens, Manish…
New Publication by Project A3
This publication reports for the first time the successful application of expansion microscopy (ExM) to fungi, allowing for visualising cellular structures with a spatial resolution of ≤60 nm with a confocal fluorescence microscope. Access to super-resolution microscopy setups is often limited, wher…