News

How do fungal infections spread in the human lung?

A chip-based infection model developed by Jena researchers enables live microscopic observation of damage to lung tissue caused by the invasive fungal infection aspergillosis. The team developed algorithms to track the spread of fungal hyphae as well as the response of immune cells. The development …

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Arts & Science: Genesis of an Artistic Fact

In summer 2021 scientists and artists come together for a unique exchange between the disciplines. The project “Entstehung einer künstlerischen Tatsache” (“Genesis of an Artistic Fact”) enables scientists to gain new perspectives on their work and artists to expand their artistic practice through sc…

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Alternative energy in the fungal cell

Until now, almost all studies suggested that the formation of hyphae is one of the most important virulence factors of the yeast Candida albicans. Ilse Jacobsen, Project leader of FungiNet Project C5 at Leibniz-HKI and her team in in Jena – in close collaboration with the group of Thomas Dandekar wi…

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TRR 124 FungiNet granted DFG funding for a further four years

The German Research Foundation (DFG) will fund the Collaborative Research Center/Transregio (CRC/TR) “FungiNet” for four more years with approximately ten million Euro. In the only CRC studying human pathogenic fungi, scientists in Jena and Würzburg will investigate infection processes and novel the…

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Cellular altruism

Candida albicans forms filaments on epithelial cells that help the fungus attach and cause infections. Infections caused by yeasts of the genus Candida trigger an immune response that was previously known only in the defense against viruses, bacteria or parasites. A research team from Jena including…

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Wissenschaftler:innen und Karriere Jena

The Deutsche Forschungsgemeinschaft (DFG) promotes equal opportunities for scientists in its programmes. In order to pool and use the equal opportunities funds of coordinated programmes for targeted and tailored measures, the association "Wissenschaftler:innen und Karriere Jena" („Scientists and Car…

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Coinfection: More than the sum of its parts

Infections with two pathogens pose a serious threat in the clinics. Researchers from Würzburg and Jena have developed a technique that provides new insights into this process and can be used as an early warning system. Organ and stem cell transplants are proven and frequently used methods in everyda…

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Antibiotics affect balance of intestinal microbiome

Treatment with antibiotics has a lasting effect on the microbiome in the digestive system. While the bacterial flora is largely regenerated within 30 to 90 days after drug treatment, its interaction with resident fungi changes. In a combination of bioinformatic analyses and laboratory experiments, a…

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Fungus delays immune response

Extracellular vesicles - small, membrane-enclosed particles secreted by cells - are important components of cell communication and interaction. For example, they transport messenger substances from cell to cell. What role they play in the interaction of the pathogenic yeast fungus Candida albicans w…

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